Vitamin D and diabetes: Does deficiency of calciferol affect blood glucose level? | The Times of India


Though several studies have worked on it, the outcome has mostly been poorly understood.

In a study held in Japan with 1256 adults with prediabetes to an active form of vitamin D analogue (eldecalcitol) or placebo, the risk of diabetes was also lower in the vitamin D group than in the placebo group, but the difference was again not significant.

“Vitamin D may play a role in type 2 diabetes; however, to better define the role of vitamin D in the development and progression of type 2 diabetes, high-quality observational studies and RCTs that measure blood 25-hydroxyvitamin D concentration and clinically relevant glycemic outcomes are needed,” a review article published in the Nature says.

A 2021 study published in Frontiers in Endocrinology found that the recommended doses of vitamin D significantly decreased the level of HbA1c after 3 as well as after 6 months of vitamin D supplementation in patients with type 2 diabetes treated with metformin and added that it is possible that vitamin D has beneficial effects only in vitamin D deficient patients especially in those with poor glycaemic control.



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